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News

Motif Neurotech's DOT wins FDA IDE for first clinical trial in treatment-resistant depression

The FDA has approved Motif Neurotech's investigational device exemption to begin a first-in-patient clinical trial of DOT, a millimeter-scale epidurally implanted wirelessly powered brain stimulator that targets the prefrontal cortex. The Rice University spinout, backed by former Neuralink president Max Hodak among others, becomes one of the first companies to attempt an implantable depression therapy at the size and patient-acceptance profile that has eluded every prior DBS-for-depression programme.

Apr 27, 2026 · 3 min read

Industry News

Orchestra BioMed and Medtronic move pacemaker-delivered hypertension therapy toward pivotal readout

MODERATO II data presented at Heart Rhythm 2026 shows AVIM Therapy — bioelectronic blood pressure control delivered through a standard dual-chamber pacemaker — produced an 8.1 mmHg net reduction in 24-hour ambulatory systolic BP at six months, with the Medtronic-partnered BACKBEAT pivotal trial now actively enrolling under an FDA-amended protocol.

Apr 27 · 3 min read

Market Moves

China issues guided pricing for invasive BCI procedures as provinces begin reimbursement roll-out

China's National Healthcare Security Administration has set government-guided prices of 6,000–6,600 yuan per invasive brain-computer interface implantation procedure, with Sichuan, Hubei and Zhejiang now attaching fee schedules at the provincial level — moving the country further ahead of the United States on the reimbursement layer that will decide whether BCIs scale as routine medicine.

Apr 23 · 3 min read

Industry News

FDA signals long-horizon regulatory commitment as CorTec joins Total Product Life Cycle Advisory Program

Two weeks after securing Breakthrough Device Designation for stroke rehabilitation, CorTec has been accepted into the FDA's TAP — a dedicated advisory track that pairs the German neurotech company with an agency liaison and early engagement with CMS, signalling an unusually long regulatory horizon for an implanted brain-computer interface.

Apr 23 · 3 min read

Research

Macaque BCI Navigates Virtual Forest With a Single Fixed Decoder Across Task Switches

A KU Leuven team led by Peter Janssen trained three rhesus macaques to pilot avatars through virtual environments using implanted multi-array BCIs, with premotor cortex outperforming primary motor cortex and a single fixed decoder generalising across perspectives, avatars, and dynamic targets.

Apr 22 · 4 min read

Industry News

Maharbiz Launches Epia Neuro, a Stroke-Focused BCI Built for Lifelong Assistive Use

Michel Maharbiz departed iota Biosciences on 1 April and has emerged with a San Francisco BCI startup targeting post-stroke upper-limb rehabilitation, with a 64-channel epidural array, motorised glove, first-in-human at Lenox Hill later this year, and an FDA submission targeted for February 2027.

Apr 22 · 4 min read

Research

Northwestern Prints Artificial Neurons That Fire Action Potentials Into Live Brain Tissue

A Mark Hersam-led team at Northwestern has demonstrated aerosol-jet-printed neuromorphic devices that generate biologically realistic voltage spikes and trigger responses in mouse cerebellum slices, a first for printed electronics and a potential route to lower-cost, flexible neural interfaces.

Apr 22 · 3 min read

Research

INBRAIN Completes Enrolment in World's First-in-Human Graphene Brain-Computer Interface Study

The Barcelona neurotechnology enrolled ten patients and implanted eight during brain tumour resection at Salford Royal Hospital, completing the first human cohort for any graphene-based neural interface. Full results due later in 2026.

Apr 21 · 3 min read

Market Moves

ONWARD Medical Raises €40.6m to Scale ARC Therapy Rollout and Fund Implantable Pipeline

The Eindhoven-listed neurotech priced a private placement at €3.00 per share, led by EQT Life Sciences, to expand ARC-EX commercial operations and advance ARC-IM through regulatory work. Cash runway extends into Q1 2028.

Apr 20 · 4 min read

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